A connection between stress and cancer?

If you know me, and I believe you do, you know I have an interest in mind/body medicine which argues that calming the mind can have beneficial effects on the body. There’s a lot of anecdotal evidence making this case but not a great understanding on how this process could work. This article from the Harvard Medical School notes the following.

A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital and Beth Israel Deaconess Medical Center finds that eliciting the relaxation response—a physiologic state of deep rest induced by practices such as meditation, yoga, deep breathing and prayer—produces immediate changes in the expression of genes involved in immune function, energy metabolism and insulin secretion.

A systems biology analysis of known interactions among the proteins produced by the affected genes revealed that pathways involved with energy metabolism, particularly the function of mitochondria, were upregulated during the relaxation response. Pathways controlled by activation of a protein called NF-κB—known to have a prominent role in inflammation, stress, trauma and cancer—were suppressed after relaxation response elicitation. The expression of genes involved in insulin pathways was also significantly altered.

I read that and said, “Hold on! Cancer?” Many people have theorized about a connection between stress and cancer but until now I’ve never seen any real science to back this up. I’ll be interested to hear what more research brings.

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